Diversity of two-component systems: insights into the signal transduction mechanism by the Staphylococcus aureus two-component system GraSR
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Diversity of two-component systems: insights into the signal transduction mechanism by the Staphylococcus aureus two-component system GraSR
The response to cationic antimicrobial peptides (CAMPs) in Staphylococcus aureus relies on a two-component system (TCS), GraSR, an auxiliary protein GraX and an ATP-binding cassette (ABC) transporter, VraF/G. To understand the signal transduction mechanism by GraSR, we investigated the kinase activity of the cytoplasmic domain of histidine kinase GraS and the interaction with its cognate respon...
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ژورنال
عنوان ژورنال: F1000Research
سال: 2014
ISSN: 2046-1402
DOI: 10.12688/f1000research.5512.1